The Health Benefits of Magnesium Malate

Benefits, Side Effects, Dosage, and Interactions

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You may be familiar with supplement enthusiasts singing the praises of magnesium, and for good reason. Magnesium is important in the human body because it can support the muscles, aid in bone health, and even alleviate migraines and anxiety symptoms.

Many types of magnesium are available and they all have their own unique traits and suit various needs.

There are at least 10 varieties available to consumers today, from the common magnesium citrate supplements that are easily absorbed in the body to the oral magnesium chloride geared toward digestive upset.

Then there’s magnesium malate. According to Willow Jarosh, MS, RD, the owner of Willow Jarosh Culinary Nutrition, "Magnesium malate is a compound of magnesium and malic acid, as opposed to other forms of magnesium that are compounds of magnesium and things like citric acid (magnesium citrate) or glycine (magnesium glycinate)."

Jarosh adds that magnesium malate is similar to other forms in that it provides magnesium to your body. "Mostly, the different forms differ by how well our bodies can absorb them."

She goes on to say that there was a study done in mice which found that magnesium malate was more rapidly absorbed and kept blood levels of magnesium higher for longer. Many consider it to be the most bioavailable magnesium.

Health Benefits

There are many benefits of magnesium malate as magnesium plays a significant role in various bodily functions.

Willow Jarosh, MS, RD

Magnesium is incredibly important in the body. The benefits of magnesium malate are similar to that of other forms of magnesium—raising magnesium levels in the blood.

— Willow Jarosh, MS, RD

Although it’s involved in hundreds of processes in the body, there are some main benefits to keep in mind when taking magnesium malate.

Protein Synthesis

Creating proteins in the body is crucial in the work that cells do. Proteins are the big molecules that help the body function at its very best, regulating tissues and organs along the way.

Magnesium is a key player in the DNA that’s needed to create these proteins, which means taking magnesium malate can make your body work at its most optimal, down to the cells, proteins, and DNA.

Studies have confirmed this role of magnesium, like one early study from 1985 that states, “The results are consistent with a role for intracellular magnesium in the regulation of protein synthesis and support the hypothesis that magnesium has a central role in the regulation of metabolism and growth.”

Muscle Function

Magnesium malate can help the muscles perform better, assisting them in contraction and relaxation. It’s even instrumental in building muscle.

Studies have confirmed this benefit of magnesium, such as one from 2006 which proved that magnesium boosted muscle performance, grip strength, lower-leg muscle power, knee extension torque, and ankle extension strength in older adults.

Nerve Function

It’s been found that magnesium malate can help transmit information from the brain to the rest of the body.

This means that it can aid in a number of neurological disorders, such as, according to a 2018 study, “migraine, chronic pain, epilepsy, Alzheimer’s, Parkinson’s, and stroke, as well as the commonly comorbid conditions of anxiety and depression.”

Bone Development

Magnesium is a top contributor to bone stabilization, growth, and mineralization, which can prevent diseases like osteoporosis.

As a 2013 study points out, controlling and maintaining what’s called “magnesium homeostasis” can “maintain bone integrity.”

Possible Side Effects

Jarosh lays out the potential side effects of magnesium malate, saying, “Getting too much magnesium from food isn’t a risk, since our bodies eliminate excess dietary magnesium via our kidneys.

While high amounts of magnesium from food sources isn't a problem, Jarosh notes that, "You can take large doses of supplemental magnesium" which can "lead to diarrhea, nausea, and abdominal cramping.”

Always consult with your doctor before taking any new supplement, including magnesium malate.

Dosage and Preparation

Your doctor can recommend an ideal magnesium malate dosage for you based upon how much magnesium is already in your body (which can be discovered from a blood test) and your unique needs, but generally, this is the recommended dosage, according to Jarosh.

Daily Recommended Magnesium Dosage

According to Jarosh, the daily recommendation for magnesium is as follows:

  • 400mg for men between the ages of 19 and 30
  • 310mg for women between the ages of 19 and 30
  • 420mg for men aged 31 to 50 and older
  • 320mg for woman aged 31 to 50 and older

Magnesium malate supplements are commonly taken orally with a meal, but you can also get magnesium from food sources.

As Jarosh explains, one ounce of pumpkin seeds contains 156mg of magnesium. One ounce of almonds contains 80mg of magesium. “Most nuts, seeds, and beans contain some magnesium,” she adds.

Jarosh also notes that, "If someone’s medical professional thinks they may not be getting enough magnesium, and they couldn’t get it from food sources, a supplement may be indicated. But the dosage and frequency would need to be personalized to that person’s needs."

Be sure to check with your doctor and/or pharmacist regarding drug interactions when taking magnesium malate. They can include certain diuretics, antibiotics, and anti-diabetes medications.

What to Look For

Magnesium malate supplements are available over the counter in a variety of dosages. It’s commonly made by natural supplement brands, including:

Third-Party Testing

Jarosh adds, “If someone is going to take a supplement, magnesium malate or others, I always recommend purchasing from a brand who does third-party testing to ensure purity.”

5 Sources
Verywell Fit uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. Uysal N, Kizildag S, Yuce Z, et al. Timeline (bioavailability) of magnesium compounds in hours: Which magnesium compound works best?. Biol Trace Elem Res. 2019;187(1):128-136.

  2. Terasaki M, Rubin H. Evidence that intracellular magnesium is present in cells at a regulatory concentration for protein synthesis. Proc Natl Acad Sci U S A. 1985;82(21):7324-7326.

  3. Dominguez LJ, Barbagallo M, Lauretani F, et al. Magnesium and muscle performance in older persons: the InCHIANTI study. Am J Clin Nutr. 2006;84(2):419-426.

  4. Kirkland A, Sarlo G, Holton K. The role of magnesium in neurological disorders. Nutrients. 2018;10(6):730.

  5. Castiglioni S, Cazzaniga A, Albisetti W, Maier JAM. Magnesium and osteoporosis: current state of knowledge and future research directions. Nutrients. 2013;5(8):3022-3033.

By Shelby Deering
Shelby Deering is a lifestyle writer based in Madison, Wisconsin. She specializes in the connection between exercise and the mind, calming movement-based exercise like yoga, and running.