The Benefits of Tyrosine

Tyrosine is an amino acid that your body produces from phenylalanine (another type of amino acid). Also found in a number of foods (including meat, fish, eggs, dairy, eggs, nuts, legumes, and oats), tyrosine is available in dietary supplement form as well.

Tyrosine is essential to your body's production of melanin (a type of pigment) and several key brain chemicals (including dopamine and norepinephrine). It also plays an important role in the function of the adrenal, thyroid, and pituitary glands, which are involved in producing and regulating your hormones.

One of the most common uses of tyrosine supplements is the treatment of a genetic disorder known as phenylketonuria. In people with phenylketonuria, the body is unable to process phenylalanine properly and, as a result, cannot produce the tyrosine it needs to function.

In alternative medicine, tyrosine supplements are often touted as a natural remedy for a range of health problems, including:

• Alzheimer's disease
• Attention Deficit Hyperactivity Disorder
• Chronic fatigue syndrome
• Depression
• Heart disease
• Parkinson's disease
• Premenstrual syndrome
• Stress
• Stroke

Some alternative medicine proponents claim that tyrosine supplements can also help suppress appetite, promote weight loss, increase mental alertness, improve memory, and enhance athletic performance.

Although relatively few studies have tested the effects of taking tyrosine supplements, there's some evidence that tyrosine may offer certain health benefits. Here's a look at several key findings from the available research:

1) Phenylketonuria

For a report published in the Cochrane Database of Systematic Reviews in 2010, investigators analyzed the available clinical trials on the use of tyrosine supplements in people with phenylketonuria. Looking at data from six clinical trials with a total of 56 phenylketonuria patients, the report's authors found that blood levels of tyrosine were significantly higher in participants receiving tyrosine supplements (compared to those given a placebo). However, the authors note that more studies are needed before tyrosine supplements can be recommended for the treatment of phenylketonuria.

2) Brain Function

Some studies show that use of tyrosine supplements may boost brain function under certain conditions. For instance, a 2010 study published in the Journal of the International Society of Sports Nutrition found that tyrosine supplementation led to significantly greater improvements in focus and alertness after exhaustive exercise. The study included 19 healthy college students, each of whom was given either a tyrosine supplement or a placebo for a four-week period.

In addition, a 2007 study of 19 people (published in Physiology & Behavior) found that use of tyrosine supplements helped protect against the detrimental effects of severe cold exposure on cognitive performance and memory.

3) Exercise Performance

So far, studies examining tyrosine's effects on exercise performance have yielded mixed results. In a 2011 study from the European Journal of Applied Physiology, for example, tests on eight healthy male volunteers found that consumption of a tyrosine-enriched drink helped increase endurance while exercising in the heat. However, a 2012 study published in the International Journal of Sport Nutrition and Exercise Metabolism (also involving eight male volunteers) found that tyrosine supplementation failed to protect against exhaustion while exercising in a warm environment.

More research is needed before tyrosine supplements can be recommended for enhanced exercise performance.

Since there's some concern that tyrosine may trigger migraine headaches, people prone to migraines should avoid the use of tyrosine supplements. In addition, tyrosine supplements may cause side effects like fatigue, heartburn, and nausea.

It's important to keep in mind that supplements haven't been tested for safety and dietary supplements are largely unregulated. In some cases, the product may deliver doses that differ from the specified amount for each herb. In other cases, the product may be contaminated with other substances such as metals. Also, the safety of supplements in pregnant women, nursing mothers, children, and those with medical conditions or who are taking medications has not been established. 

Widely available for purchase online, tyrosine supplements can be found in many natural-foods stores and in stores specializing in dietary supplements.

Due to the limited research, it's too soon to recommend tyrosine for any condition. It's also important to note that self-treating a condition and avoiding or delaying standard care may have serious consequences. If you're considering using tyrosine for any health purpose, make sure to consult your physician first.

_Sources

_{Hoffman JR, Ratamess NA, Gonzalez A, Beller NA, Hoffman MW, Olson M, Purpura M, Jäger R. "The effects of acute and prolonged CRAM supplementation on reaction time and subjective measures of focus and alertness in healthy college students." J Int Soc Sports Nutr. 2010 Dec 15;7:39.}

_{Mahoney CR, Castellani J, Kramer FM, Young A, Lieberman HR. "Tyrosine supplementation mitigates working memory decrements during cold exposure." Physiol Behav. 2007 Nov 23;92(4):575-82.}

_{Tumilty L, Davison G, Beckmann M, Thatcher R. "Oral tyrosine supplementation improves exercise capacity in the heat." Eur J Appl Physiol. 2011 Dec;111(12):2941-50.}

_{Watson P, Enever S, Page A, Stockwell J, Maughan RJ. "Tyrosine supplementation does not influence the capacity to perform prolonged exercise in a warm environment." Int J Sport Nutr Exerc Metab. 2012 Oct;22(5):363-73.}

_{Webster D, Wildgoose J. "Tyrosine supplementation for phenylketonuria." Cochrane Database Syst Rev. 2010 Aug 4;(8): CD001507.}

Disclaimer: The information contained on this site is intended for educational purposes only and is not a substitute for advice, diagnosis or treatment by a licensed physician. It is not meant to cover all possible precautions, drug interactions, circumstances or adverse effects. You should seek prompt medical care for any health issues and consult your doctor before using alternative medicine or making a change to your regimen.