Is Sourdough Bread Gluten-Free?

Some People Say It's Safe, Even for Those With Celiac ... But Is It?

Is sourdough bread gluten-free?. Katarina Lofgren/Maskot/Getty Images

Despite what you might have read online, sourdough bread made from one of the gluten grains (wheat, barley, or rye) is likely to make you sick if you have celiac disease or non-celiac gluten sensitivity.

The sourdough bread may have a little less gluten in it due to the fermentation process that makes it taste sour, but it won't meet anyone's definition of gluten-free, which in the U.S. is less than 20 parts per million of gluten.

A quick chemistry lesson may help.

To make sourdough bread, you add a starter culture — usually made up of various yeast strains plus lactobacilli, which are forms of friendly bacteria — to your bread dough. Then you let the whole mixture sit until the dough rises, and proceed with baking.

This starter culture makes the dough rise like conventional baker's yeast does — both cause fermentation in the dough mixture, and the gas byproducts of fermentation are what causes the dough to rise. However, the wild yeast strains and lactobacilli in the sourdough impart a denser feel and a sour taste to the bread ... hence the term "sourdough."

Why Do People Say Sourdough Is Gluten-Free?

The fermentation process for sourdough bread partially breaks down the gluten in the flour. Note that I said partially — trust me, it's not enough to render the bread even close to being gluten-free.

The buzz around sourdough as a potential option for rendering wheat-based bread gluten-free comes from some recent research.

These studies looked at whether very specific strains of sourdough lactobacilli and yeast could break down the gluten in wheat flour completely if given enough time to work their magic. This process of breaking down proteins into fragments is called hydrolysis.

In one study, people with diagnosed celiac disease were randomly assigned to one of three groups.

The first group ate pretty standard gluten-y bread, which had 80,127 parts per million of gluten in it (remember, less than 20 ppm is considered "gluten-free"). The second group ate bread with bread made with flour that had undergone the hydrolysis process "extensively" — the resulting bread had 2,480 ppm of gluten in it (better, but not good enough). And the third group ate fully hydrolyzed bread, which had 8 ppm of residual gluten in it.

Two of the six people who consumed the standard bread discontinued the study early due to renewed celiac disease symptoms, and everyone in that group had positive celiac blood tests and villous atrophy. The two people who ate the intermediate level bread with 2,480 ppm of gluten in it didn't have symptoms but did develop some villous atrophy. But the five people who ate the fully hydrolyzed bread didn't have any symptoms and didn't have clinical signs of gluten consumption, either.

Obviously, this is a very small study, and it's far from definitive. But other research does back up its conclusions. A second project looked at a small group of children and teens who had been diagnosed with celiac and who didn't have any symptoms on the gluten-free diet and reached the same conclusion: sourdough wheat bread made with this extensive fermentation process seemed to be safe, at least in that test group.

Additional research has explored which specific strains of lactobacilli and yeast might work best to break down the gluten in bread flour.

So Does This Mean I Can Eat Sourdough Bread?

No, definitely not! As I said, these studies used a specific hydrolysis process created with specially bred strains of yeast and lactobacilli, and it's not being offered commercially. This is not something you'd be able to try at home, either.

The clinicians involved in these studies have said more research is necessary before they can declare this type of hydrolyzed sourdough bread safe for people with celiac disease.

However, interest in this subject is high, so it's entirely possible that we'll see gluten-removed wheat-based sourdough bread on store shelves at some point.


DiCagno R. et al. Gluten-free sourdough wheat baked goods appear safe for young celiac patients: a pilot study. Journal of Pediatric Gastroenterology and Nutrition. 2010 Dec;51(6):777-83. doi: 10.1097/MPG.0b013e3181f22ba4.

DiCagno R. et al. Use of selected sourdough strains of Lactobacillus for removing gluten and enhancing the nutritional properties of gluten-free bread. Journal of Food Protection. 2008 Jul;71(7):1491-5.

Greco L. et al. Safety for patients with celiac disease of baked goods made of wheat flour hydrolyzed during food processing. Clinical Gastroenterology and Hepatology. 2011 Jan;9(1):24-9. doi: 10.1016/j.cgh.2010.09.025. Epub 2010 Oct 15.