The 10 Best Mushroom Supplements of 2020

Boost your overall health

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Our Top Picks
"A combination of the three most beneficial medicinal mushrooms."
"All mushrooms are non-GMO verified."
"Helps boost your immunity and reduce fatigue."
"Each serving is packed with organic lion’s mane mushroom extract."
"Cooks well into soups and sauces."
"Made of organically grown mushrooms with no artificial colors."
"Rich in antioxidants, and vitamins B and C."
"Contains antioxidants that can reduce low-density lipoprotein."
Best Cordyceps:
NOW Cordyceps at Amazon
"Offers antioxidant and anti-inflammatory benefits."
"Used to fight mental and physical fatigue."

Best Overall: The Genius Brand Genius Mushrooms Supplement

A combination of the three most beneficial medicinal mushrooms, Genius Mushrooms gets our top ranking due to its high-quality ingredients, exceptional value, and effectiveness. Rather than taking separate supplements of lion’s mane, reishi, and cordyceps mushrooms, you can get the benefits of all three in one convenient supplement. This potent formula may help you enhance mental clarity and focus, boost immune function, and improve natural energy and endurance. Made of organic mushrooms harvested in the U.S, these supplements are third-party tested to ensure purity.

Best Overall Runner-Up: New Chapter Reishi Mushroom LifeShield Immune Support

For a boost to your immunity and overall wellness every day, try this mushroom immune support supplement from New Chapter. With a blend of mushrooms, including reishi, lion’s mane, shiitake, and Poria, the formula is designed to deliver powerful nutrients from the mushrooms’ body and spores. All mushrooms are non-GMO verified, 100% vegan, and grown in the U.S. under certified organic measures.

Best Budget: Swanson Triple Mushroom Complex

The powerful combination of shiitake, reishi, and maitake mushrooms can help boost immunity and reduce fatigue in this super affordable, high-quality supplement from Swanson. It’s made of 100% pure mushrooms that are sourced from their native location, tested for purity and safety and manufactured under the strictest quality controls. You can swallow the capsules or open them and pour the powder into hot tea or other beverages. If you’d like to give medicinal mushrooms a try but don’t want to make a big commitment, this supplement is a solid choice.

Best Powder: Four Sigma Foods Lion's Mane Mushroom Elixir,

Lion’s mane mushrooms are large, white, shaggy mushrooms that look like a lion’s mane as they grow. They contain bioactive substances and some research indicates that they can improve memory, boost creativity, and help with concentration. Fans of this Four Sigmatic lion’s mane mushroom elixir like to use to help kick start their productivity and push through periods of brain fog.

Made of all-natural ingredients, each serving is packed with 1500mg of organic lion’s mane mushroom extract, along with rose hips for vitamin C, organic Rhodiola to support memory, and organic mint and stevia for flavor. It easily mixes into hot water and tastes great in your favorite coffee, tea, or smoothies.

Best Blend: Naturealm 7 Mushroom Extract Powder

If you’re looking for a mushroom supplement that pairs well with lots of foods and drinks, a blend may be your best bet. The combination of the seven mushrooms in this Sacred 7 mushroom extract powder makes an earthy, malty flavor that tastes great in smoothies, coffee, tea, yogurt, and oatmeal.

The powder is very fine and fresh, so it also blends easily and cooks well into soups and sauces. This versatile, convenient supplement is an easy way to enhance your foods and drinks with a nutrition-packed, immunity-boosting superfood. Although it’s more expensive than some other mushroom blend supplements, users say it’s well worth the cost.

Best Organic: Garden of Life RM-10 Immune System Food Organically Grown Mushrooms

Another powerful mushroom blend, this supplement from Garden of Life is made of 10 organically grown, tonic mushrooms for immune system support. It also contains Cat's Claw and a highly absorbable form of selenium, to support immune cell function and response. Made with no artificial colors or preservatives, this supplement is vegetarian, gluten-free, and dairy-free.

Best Maitake: Host Defense Maitake Capsules

Rich in antioxidants and vitamins B and C, as well as other nutrients, maitake mushrooms have shown to have a positive effect on overall immunity. Some research suggests that it may be effective in treating certain illnesses and conditions such as cancer, type 2 diabetes, and high cholesterol.

Host Defense Maitake supplement uses organic mushrooms that are farmed using sustainable methods. Although maitake is usually well-tolerated, you may want to start with one capsule rather than the recommended two to make sure you don’t have any side effects such as stomach or digestive issues.

Best Chaga: Micro Ingredients Organic Chaga Mushroom Extract 100:1 Powder

A nutrient-dense superfood, Chaga mushrooms are rich in a wide variety of vitamins, minerals, and nutrients, including B-complex vitamins, vitamin D, potassium, amino acids, fiber, iron, and contain many antioxidants that may reduce low-density lipoprotein (LDL), the so-called "bad" cholesterol, and improve overall heart health.

With plenty of antioxidants, they’re also a contender for fighting inflammation and boosting immunity. This organic Chaga powder is non-GMO and contains no additives, preservatives, fillers, or artificial flavors and colors. It’s easy to mix into juice, a smoothie, or plain water. 

Best Cordyceps: NOW Cordyceps 750mg

A type of medicinal mushroom believed to offer antioxidant and anti-inflammatory benefits, cordyceps is a genus of parasitic fungi that grows on the larvae of insects. The remains of the insect and fungi have been dried and used in traditional Chinese medicine for centuries to increase energy, treat asthma, support the liver and kidney, and improve sex drive.

Much of the scientific research about the benefits of cordyceps is limited to animal or lab studies, so experts currently can’t draw definitive conclusions about their effects on people. However, potential health benefits include energy and endurance improvement, enhanced athletic performance, help with diabetes management, and heart health benefits. Some studies also suggest that cordyceps can protect against health problems including asthma, depression, diabetes, and upper respiratory tract infections. Made with organic cordyceps, these vegan capsules are an easy way to get your daily dose at an affordable price.

Best Reishi: Anima Mundi Apothecary Immortality 7 Mushroom Superfood Blend with Cacao

Reishi mushrooms have been used for centuries to support the immune system, help combat mental and physical fatigue, and reduce the natural aging process. Known for their woody, slightly bitter taste, they’re rarely used in cooking but are popular in teas or medicinal tonics. This sustainable and organically grown Anima Mundi Reishi mushroom powder is easy to add to smoothies, teas, coffee, or even just plain warm water, and may help you feel more energized throughout the day.

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