Supplements The 7 Best Multivitamins for Men of 2023 Researched-backed multivitamins to support men's health By Peter Pace, MS, RD, CSCS Peter Pace, MS, RD, CSCS Peter is a highly sought-after nutritionist and fitness trainer with nationally recognized credentials and certifications in both sectors of health. Learn about our editorial process Updated on April 21, 2023 Medically reviewed Verywell Fit articles are reviewed by board-certified physicians and nutrition and exercise healthcare professionals. Medical Reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more. by Barbie Cervoni MS, RD, CDCES, CDN Medically reviewed by Barbie Cervoni MS, RD, CDCES, CDN Facebook LinkedIn Twitter Barbie Cervoni MS, RD, CDCES, CDN, is a registered dietitian and certified diabetes care and education specialist. Learn about our Medical Review Board Fact checked Verywell Fit content is rigorously reviewed by a team of qualified and experienced fact checkers. Fact checkers review articles for factual accuracy, relevance, and timeliness. We rely on the most current and reputable sources, which are cited in the text and listed at the bottom of each article. Content is fact checked after it has been edited and before publication. Learn more. by Autumn Rauchwerk, MS, RDN, E-RYT Print We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation. Learn more. A men’s multivitamin may be beneficial if you have a nutrient deficiency, or if you have difficulty meeting your daily recommended intakes from food alone. Individuals that may benefit from a multivitamin include, those that follow a restricted diet, those with increased needs due to high levels of physical activity, and those that are on certain medications or have certain diseases that affect vitamin and mineral levels. Almost one-third of the U.S. population may be at risk for deficiency in at least one vitamin. While this may seem like a logical case for the use of a multivitamin, it highlights a need for us to eat more nutritious foods. As Registered Dietitian Kyala Clegg, MS, RD, CSCS, CES, says, “no matter the quality of the supplement, you cannot out-supplement an inadequate diet.” Keep in mind that while multivitamin use may reduce your risk for a deficiency in certain key vitamins, it also may contribute to a risk of dangerously high intakes of other nutrients. It also likely does not prevent chronic diseases. When choosing a multivitamin, we prioritized ones that are third-party tested, preferably by NSF, ConsumerLab.com, or USP, to ensure for purity and potency. We evaluated multivitamins for nutrients particularly important for men including zinc and selenium, and ones that limited nutrients men do not typically need to supplement, including iron. We also considered the nutritional needs of different ages, as well as price, dosage, complete nutrition profile, and added ingredients. Editor's Note Our team of registered dietitians reviews and evaluates every single supplement we recommend according to our dietary supplement methodology. From there, a registered dietitian on our Expert Review Board reviews each article for scientific accuracy. Always speak with a healthcare professional before adding a supplement to your routine to ensure that the supplement is appropriate for your individual needs, and to find out what dosage to take. Jiaqi Zhou / Verywell Our Top Picks Best Overall: Thorne Research Basic Nutrients 2/Day at Amazon Jump to Review Best Budget-Friendly : Nature Made Multi for Him at Amazon Jump to Review Best Gummy: SmartyPants Men's Formula at Amazon Jump to Review Best for Older Men: Garden of Life mykind Organic Men's 40+ at Amazon Jump to Review Best Subscription: Ritual Men Multivitamin 18+ at Amazon Jump to Review Best Personalized : Care/of Multivitamin at Takecareof.com Jump to Review Best Organic & Vegan: Garden of Life mykind Organics Men's Once Daily Multi at Amazon Jump to Review In This Article Expand Our Picks Are Multivitamins for Men Beneficial? Who May Not Benefit from a Men’s Multivitamin How We Select Supplements What to Look For in a Men's Multivitamin FAQ Best Overall Thorne Research Basic Nutrients 2/Day Thorne View On Amazon View On Findyourhealthyplace.com View On Pureformulas.com Pros NSF Certified for Sport option available Capsule form Highly absorbable forms of vitamins and minerals Cons Expensive We like Thorne because they are committed to following and evolving with science, and their Basic Nutrient 2/Day takes our top pick because of the nutrients it packs into two small, easy-to-take capsules. They also have their own manufacturing facility and in-house testing labs where many of their supplements are made and inspected for quality assurance. Thorne offers their Basic Nutrients 2/Day in an NSF Certified for Sport version for a reasonable markup in price, which is the best option for athletes. This buys you third-party assurance that it contains what it says it contains without contaminants and does not contain any substances prohibited by major athletic organizations. With smaller capsules compared to other options, this multivitamin may be easier to swallow. You may also find the capsule form makes it easier to digest. You can best maximize absorption by splitting up the two-capsule serving so that you take one with a meal earlier in the day and the other at your evening meal. In this formula, you will find methylated B12 and folate, which are their naturally occurring forms that may be more effectively utilized by the body. It also contains both vitamin K1 and K2, which many people may benefit from supplementing. Price at time of publication: $36 for 60 count ($1.20 per serving) Key specs:Serving size: 2 capsules | Servings per container: 30 | Major vitamin(s) missing: None | Major mineral(s) missing: Iron, potassium | Free from: Gluten, dairy, soy, and artificial colors/preservatives Best Budget-Friendly Nature Made Multi for Him Amazon View On Amazon View On Naturemade.com Pros USP Verified Single tablet dosage Affordable Cons Does not contain methylated forms of B vitamins Contains gelatin; not suitable for vegans and vegetarians Nature Made is a trusted brand that comes at a more affordable price point. The Multi for Him supplement is third-party tested for purity and potency, and USP Verified. It includes 22 key nutrients for daily nutritional support, at dosages appropriate for a baseline multivitamin, all in one daily tablet. We also like that it omits iron, a mineral that most men do not need to supplement. Nature Made Multi for Him provides adequate amounts of B-vitamins, but not in the more absorbable, methylated forms. Also, this product does contain gelatin, so it is not suitable for those following a vegan or vegetarian diet. It also contains additives including modified food starch, maltodextrin and polyethylene glycol. Price at time of publication: $9 for 90 count ($0.10 per serving) Key specs:Serving size: 1 tablet | Servings per container: 90 | Major vitamin(s) missing: None | Major mineral(s) missing: iron, potassium | Free from: Gluten and artificial flavors and colors Best Gummy SmartyPants Men's Formula Smarty Pants Vitamins View On Amazon View On Walmart View On Bed Bath & Beyond Pros NSF Certified Contains omega-3s Free of common food allergens Cons Large serving size (6 gummies) Contains 6 grams of added sugar If you're looking for a gummy multivitamin option, try SmartyPants Men's Formula. This supplement is third-party tested for purity and potency and is NSF Certified, making it a trusted product. We like that it contains the active, methylated forms of B vitamins and adequate dosages of key nutrients for men, without iron. This multi is also free of common food allergens including milk, eggs, shellfish, soy, peanuts, tree nuts, wheat. We like that this multivitamin contains 510 milligrams of fish oil with 125 milligrams combined of omega-3s EPA and DHA. Omega-3s can help to lower inflammation and support brain, eye and heart health. This is a relatively low dose, given the recommended intake of 1,600 milligrams of omega-3s per day for adult men, but it's a helpful way to help boost your daily intake. Also of note, they source their fish oil from sustainable fisheries and only use small fish, limiting mercury exposure. One serving is 6 gummies, which can be a lot to take everyday. However, they are enjoyable to eat, with a sweet and fruity flavor. They are sweetened with organic cane sugar and contain natural flavors and colorings from organic carrots, berries and turmeric. Each serving does contain 6 grams of sugar, which may be of significance for those managing their blood sugar. Price at time of publication: $26 for 180 count ($0.86 per serving) Key specs:Serving size: 6 gummies | Servings per container: 30 | Major vitamin(s) missing: None | Major mineral(s) missing: iron, potassium, calcium, magnesium | Free from: Gluten, milk, eggs, shellfish, soy, peanuts, tree nuts, wheat, and artificial colorings and flavorings The 7 Best Fish Oil Supplements of 2023 Best for Older Men Garden of Life mykind Organic Men's 40+ Amazon View On Amazon View On Walmart View On Everyhealth.com Pros Organic Made from a whole food blend Certified gluten-free Cons Expensive Larger tablet form Not third-party certified Garden of Life didn’t venture too far off from their mykind Organics Men’s Once Daily in this formulation designed for older men. It’s still made from over 30 organic fruits, vegetables, and herbs, and it has the same certifications and is offered in a more affordable 60-serving option. It does, however, differ in the amount of vitamins, minerals, and extra ingredients it has. For example, it has over three times the amount of vitamin B12, which is a common deficiency for older people. It also has vitamin K2 added, which has been shown to play an important role in heart and bone health. The extra blend of food ingredients, which include pomegranate, pumpkin, turmeric, and lycopene, all have some evidence to suggest a protective effect on prostate and heart health. As we age, our needs change, and that change is unique to each of us. That is why we recommend you speak with a healthcare provider before taking a multivitamin marketed toward older individuals. Price at time of publication: $56 for 120 count ($0.93 per serving) Key specs:Serving size: 2 tablet | Servings per container: 60 | Major vitamin(s) missing: None | Major mineral(s) missing: Calcium, iron, potassium, magnesium | Free from: Gluten, soy, dairy, and artificial colors/preservatives The 11 Best Protein Powders for Men of 2023, According to a Dietitian Best Subscription Ritual Essential for Men Multivitamin 18+ Amazon View On Amazon View On Ritual.com Pros Third-party tested Transparency of ingredient sourcing Includes methylated forms of B vitamins Cons Subscription only Does not include all essential micronutrients Ritual Men's Multivitamin 18+ is designed to target common nutrient deficiencies in men's diets. They provide a breakdown of where each ingredient is sourced from and also utilize third-party testing for purity, potency and composition as well as for heavy metals and other contaminants. You'll notice that they leave out certain ingredients including calcium, vitamin C, copper, iron and selenium which most men are able to get adequate amounts of from diet alone. Men have lower iron needs than women, with an RDA of 8 milligrams compared to 18-27 milligrams for women, so supplementation of iron is typically not needed for men. However, if you are deficient in any of these vitamins and minerals, you make want to consider additional supplementation to target your needs. The delayed release, stomach-acid resistant capsule makes the vitamin gentle on an empty stomach and optimize absorption. The capsule is made from plant-based ingredients, making it suitable for vegans. We also like that it includes omega-3 DHA sourced from micro-algae. Price at time of publication: $33 for 60 count ($1.10 per serving) Key specs:Serving size: 2 capsules | Servings per container: 30 | Major vitamin(s) missing: Vitamin C | Major mineral(s) missing: Iron, copper, selenium, calcium, potassium | Free from: Gluten, dairy, soy, and artificial colors/preservatives The 12 Best Supplements, According to a Dietitian Best Personalized Care/of Multivitamin View On Takecareof.com Pros Has an in-depth, evidence-based questionnaire to help guide your supplement selections Offers customizable supplement packets All supplements are internally and third-party tested Cons Subscription only Limited information provided on ingredient sourcing and third-party testing information Care/of is a subscription-based service that allows you to curate your own customizable daily supplement packets and conveniently have them delivered to your door monthly. We also like that all of their supplements are both internally and third-party tested for purity and potency. Their multivitamin offers a base of key vitamins A, C, D3, E, B6, B12, and K as well as choline, calcium, magnesium, and potassium. You have the option to add additional vitamin, minerals as well as herbal supplements, and probiotics to your daily packet. We like that they offer an in depth, evidence-based questionnaire to help guide your supplement selections. While it does not replace the advice of a healthcare professional, it is a helpful resource in determining your potential supplement needs. Price at time of publication: $15 for 60 count ($0.50 per serving) Key specs:Serving size: 2 tablets | Servings per container: 30 | Major vitamin(s) missing: some B vitamins | Major mineral(s) missing: Iron, copper, selenium | Free from: Egg, Fish, Milk, Peanut, Sesame, Shellfish, Soy, Tree Nuts, Wheat and artificial colors/preservatives Best Organic & Vegan Garden of Life mykind Organics Men's Once Daily Multi Amazon View On Amazon View On IHerb View On Vitamin Shoppe Pros Organic and gluten-free Made from a whole food blend NSF certified Cons Expensive Larger tablet If you're looking for an organic and vegan multivitamin, then mykind Organics Men’s Once Daily multivitamin from Garden of Life may be for you. It’s made from over 30 organic fruits, vegetables, and herbs. This multivitamin is USDA Organic, non-GMO verified, NSF Certified Gluten-Free, and certified vegan. It is also third-party certified by NSF, which ensures it contains the nutrients it says it contains without harmful contaminants. These third-party verifications provide some peace of mind that this multivitamin undergoes steps to ensure a higher quality offering. They also offer a larger container with 60 servings to make it more affordable. The list of organic food ingredients is extensive, so read it carefully to be sure you do not have any intolerances or allergies and that none of the ingredients will interact with any of your existing medications or supplements. Garden of Life is a certified B Corporation, which means it is guided by some ethical and sustainability principles. However, it may be worth noting that Garden of Life was bought by Nestle in 2017. Price at time of publication: $38 for 60 count ($0.63 per serving) Key specs:Serving size: 1 tablet | Servings per container: 60 | Major vitamin(s) missing: None | Major mineral(s) missing: Calcium, iron, potassium, magnesium, iodine | Free from: Gluten, soy, dairy, and artificial colors/preservatives Are Multivitamins for Men Beneficial? You may benefit from a vitamin and/or mineral supplement if you have, or are at risk of, a deficiency. We recommend that you work with a medical provider to identify potential vitamin or mineral deficiencies via laboratory testing like blood work. This would allow you to have a supplement approach specific to your needs. Realistically, this is not common practice in our healthcare system, so if you think you might be deficient in one or several vitamins or minerals, you may have to advocate for yourself to be tested. “Oftentimes multivitamins alone aren’t enough to reverse a deficiency. That is why if someone suspects they are deficient in a vitamin or mineral, it’s crucial to meet with a qualified dietitian to develop a plan of action that works and is backed by science,” says Crystal Pace, MS, RD, IFNCP, RYT. Men who may not be meeting their micronutrient requirements or who are at risk for a deficiency include: Those restricting energy intake for weight loss Those with reduced intake related to poor appetite or illness Those following strict dietary protocols, such as the ketogenic diet, vegan, low FODMAP, and carnivore diets Those with increased needs related to physical pursuits, such as athletes and those who work jobs requiring long and/or extreme bouts of manual labor Those with a gastrointestinal (GI) disease or who have undergone GI surgery, including bariatric surgery Those with very high alcohol intakes or who have alcohol use disorder Those on micronutrient-depleting medications The following medications are considered micronutrient-depleting and may deplete the corresponding nutrients: Proton Pump Inhibitors: may deplete B12 and magnesiumNSAIDs (Aspirin): may deplete vitamin CAnti-Hypertensives (Diuretics): may deplete calciumStatins: may deplete coenzyme Q10Metformin: may deplete B12Corticosteroids: may deplete calcium, vitamin D, potassiumBronchodilators: may deplete calcium, vitamin D Who May Not Benefit from a Men’s Multivitamin The different vitamins and minerals found in a particular whole food (a fruit or vegetable, for example) work together in ways we are only beginning to understand. Because of this, there are numerous benefits to getting our nutrients from eating a wide variety of whole foods. Scientists are calling the complex relationship of all the various components that make up a whole food the food matrix. While some supplement companies try to pack in all of these nutrients in their multivitamins, we don't know if this will ever be as effective as getting our nutrients from food as nature intended. Given the lack of scientific evidence, the Academy of Nutrition and Dietetics does not recommend the routine use of multivitamins for preventing chronic diseases without first carefully weighing the risks and benefits. Those who may not benefit from a men's multivitamin include: Those who eat a varied diet and don't have health issues: If you are not vegetarian or vegan, eat a variety of nutrient-dense foods, and have no medical indication for extra vitamins and minerals, there is probably no need to add the expense of a multivitamin. Those on certain medications: Multivitamins can influence the dosage and effectiveness of your medication. For example, vitamin K could reduce the effectiveness of your blood thinner as your body utilizes it to assist with blood clotting. Vitamin E, on the other hand, inhibits blood clotting and may increase your risk of bleeding if you are on a blood thinner. If you are taking any medications, check with a healthcare provider before starting a multivitamin. How We Select Supplements Our team works hard to be transparent about why we recommend certain supplements; you can read more about our dietary supplement methodology here. To help come up with this list, we consulted with experts Kyala Clegg, MS, RD, CSCS, CES, and Crystal Pace, MS, RD, IFNCP, RYT. We support supplements that are evidence-based and rooted in science. We value certain product attributes that we find to be associated with the highest quality products. We prioritize products that are third-party tested and certified by one of three independent, third-party certifiers: USP, NSF, or ConsumerLabs. It's important to note that the FDA does not review dietary supplements for safety and effectiveness before they go to market. Our team of experts has created a detailed, science-backed methodology to choose the supplements we recommend. What to Look For in a Men's Multivitamin The bottom line is that multivitamins don’t account for our unique individual nutrient needs. Our nutrient needs vary based on factors such as our age, genetics, health status, environment, and level of activity. Therefore, most multivitamins are more of a “shotgun” approach to ensuring that you are covering the nutritional gaps from food alone. We recommend working with a healthcare provider to determine if you need to supplement and, if so, with what nutrients. Multivitamins can vary in what vitamins and minerals they contain and to what amount of each nutrient they provide. For example, some multivitamins for men contain iron, and some do not. Men eating a variety of foods, especially red meat, may not need iron in a multivitamin. Third-Party Testing Supplements that are third-party tested are sent to a lab where they are tested to ensure they contain what they say they contain and are not contaminated with specific high-risk, common contaminants. However, it’s important to note: Third-party testing does not test to see if a product is effective or safe for everyone, and it does not ensure the supplement will not interact with other supplements or medications. Not all third-party testing is created equal. It is not uncommon for supplement companies to pay labs for certificates after conducting minimal to no testing. The third-party certifications we can trust are: ConsumerLabs, NSF, and USP. However, these certifications are difficult to obtain and/or expensive, so many companies choose not to get their products tested by one of these three organizations. Sometimes products tested by these three companies are more expensive to try to offset the cost they pay for certification.Just because a supplement is not tested by one of these three companies does not mean it’s a bad product. We recommend doing some research on the reputability of the manufacturer and calling up the manufacturer and their testing lab to determine their protocols and decide if you feel comfortable consuming the supplement. While the U.S. Food and Drug Administration (FDA) has established good manufacturing practices for dietary supplements to ensure products contain their listed ingredients in the amounts claimed and are free of contaminants, companies are responsible for meeting these requirements on their own. Therefore, the FDA will only investigate a multivitamin if someone reports that it has caused harm. Form Physical forms: You can find men’s multivitamins in capsule, tablet, gummy, liquid, and even powder form. Capsules may be better than pills to ensure greater absorption. Powdered or liquid forms may also be preferable if you have a hard time swallowing pills or have trouble with digestion (from things like gastric surgery or reflux). Another benefit of liquid variations is that you might be able to modify the dosage more easily. Nutrient forms: Supplement companies will also use different forms of each vitamin and mineral found in the multivitamin. For example: Vitamin A: Some multivitamins will have vitamin A in the form of beta-carotene, which is the plant form found in plants that your body will turn into usable vitamin A. We recommend looking for the beta-carotene form of vitamin A in your supplements, as it has the least risk of toxicity. Vitamin B12: Some multivitamins will have a synthetic form of B12 known as cyanocobalamin, while others will have a naturally occurring form known as methylcobalamin. Research shows that your body may be able to better utilize B12 as methylcobalamin and that there is some concern with B12 as cyanocobalamin because it may lead to the build-up of cyanide, a potentially dangerous chemical. Ingredients & Potential Interactions It is essential to carefully read the ingredient list and nutrition facts panel of a supplement to know which ingredients and how much of each ingredient is included relative to the recommended daily value of that ingredient. Please bring the supplement label to a healthcare provider to review the different ingredients contained in the supplement and any potential interactions between these ingredients and other supplements and medications you are taking. Many men’s multivitamins on the market today also contain additional ingredients like herbs, enzymes, and probiotics, with additional health claims that haven’t necessarily been validated through quality research. Some of those ingredients may interact with some of your medications and/or medical treatments, which is why it is vital to review supplements you are or plan on taking with a medical provider. There are many factors that contribute to how easily our bodies can use the vitamins and minerals we consume from food or supplements. Some nutrients work together, so consuming them at the same time is beneficial. Other nutrients work against each other, so it is best not to consume them at the same time. For example, calcium reduces your absorption of iron, whereas vitamin C can enhance it. According to the 2015-2020 USDA dietary guidelines for Americans, people are not consuming enough choline, magnesium, calcium, and vitamins A, D, E, and C. The 2020-2025 guidelines list calcium, potassium, and vitamin D as nutrients of a public health concern due to underconsumption from food. So, with that considered, these might be the most important nutrients to include in a multivitamin. Dosage & How Much Is Too Much? It is important to learn how to read the supplement facts label. That way, you can compare the amounts of each vitamin and mineral with the Tolerable Upper Intake Levels (UL) in order to avoid toxic intakes of any one vitamin or mineral. This will allow you to identify if a multivitamin—combined with your micronutrient intake from other sources—can be taken safely. Use this tool from ConsumerLab to help guide you. Frequently Asked Questions Are multivitamins necessary for active men? In short, no. If you are an active man, you can get all the vitamins and minerals you need to optimize your performance and well-being if you eat enough nutrient-dense foods. Studies that have provided multivitamin supplements to athletes over prolonged periods of time have shown no significant effects on performance. Should I get a specific multivitamin if I’m over 40 or 50? Yes, if you have decided to get a men’s multivitamin and are over 40 or 50 years old, it would be beneficial to look for a product that meets your evolving nutritional needs. Multivitamins marketed for men over a certain age often vary in the amounts of certain micronutrients.As we age, vitamins and minerals like calcium, magnesium, silicon, boron, and vitamins D and K become important for maintaining healthy bones. One study in older adults found that multivitamin use was associated with a 51 percent lower risk of sustaining a hip fracture.Many multivitamins in this category will also contain additional ingredients like herbs marketed for things like heart and prostate health. For instance, many will contain saw palmetto, as research has shown that it may be helpful in the treatment of benign prostatic hyperplasia (BPH). Some herbs can interact with certain medications, so be sure to check with a healthcare provider if you choose a multivitamin that contains added herbs. Remember though, that age is not the only factor that will guide you in making the right decision for yourself. Do I need to take a multivitamin every day for it to be effective? It depends. Overall, your current nutritional status and whether you have a vitamin or mineral deficiency or insufficiency will be what makes a multivitamin effective or not. If you have a micronutrient that you need to supplement, then it will be most important to take your supplement as prescribed. What is the best time to take a multivitamin? If you are looking to maximize the absorption of fat-soluble vitamins A, D, E, and K, then it is best to take your multivitamin with a source of fat from food. If you’re looking to limit the competition for absorption between vitamins and minerals, it’s better to spread your intake throughout the day, which may look different based on your unique dietary habits and schedule. There’s no one-size-fits-all approach here. What is different about a multivitamin for men versus women? The major difference you will usually find in multivitamins made for men versus women is the presence of iron and calcium, as men’s multivitamins often won’t contain them, or they will have them in lesser quantities.For reference, the recommended daily allowance (RDA) for iron in men is 8mg compared to 18mg for women prior to menopause. The RDA for calcium in men is 1,000mg versus 1,200mg for women.The other major difference will be the addition of specialty ingredients marketed specifically for “men’s health” versus “women’s health.” Supplement companies are very effective at marketing these “health benefits," which may not be based on strong scientific evidence. How much do vitamins cost monthly? The monthly cost of taking a multivitamin everyday can depend on the cost per tablet/capsule, the container size, and the recommended serving size for the supplement. A general range for a men's multivitamin cost per day is around $0.40 to $1.20 which would cost $12 to $36 every month. Some vitamin companies or websites offer the option to subscribe to buying vitamins every month with a slightly lower cost than buying a single bottle at a time. 29 Sources Verywell Fit uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Bird JK, Murphy RA, Ciappio ED, McBurney MI. Risk of Deficiency in Multiple Concurrent Micronutrients in Children and Adults in the United States. Nutrients. 2017;9(7):655. Published 2017 Jun 24. Blumberg JB, Frei BB, Fulgoni VL, Weaver CM, Zeisel SH. Impact of Frequency of Multi-Vitamin/Multi-Mineral Supplement Intake on Nutritional Adequacy and Nutrient Deficiencies in U.S. Adults. Nutrients. 2017;9(8):849. Published 2017 Aug 9. Gaziano JM, Sesso HD, Christen WG, et al. Multivitamins in the prevention of cancer in men: the Physicians' Health Study II randomized controlled trial [published correction appears in JAMA. 2014 Aug 6;312(5):560]. JAMA. 2012;308(18):1871-1880. Lim JE, Weinstein SJ, Liao LM, Sinha R, Huang J, Albanes D. Multivitamin Use and Overall and Site-Specific Cancer Risks in the National Institutes of Health-AARP Diet and Health Study. J Nutr. 2022;152(1):211-216. Kim J, Choi J, Kwon SY, et al. Association of Multivitamin and Mineral Supplementation and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis. Circ Cardiovasc Qual Outcomes. 2018;11(7):e004224. Macpherson H, Pipingas A, Pase MP. Multivitamin-multimineral supplementation and mortality: a meta-analysis of randomized controlled trials. Am J Clin Nutr. 2013;97(2):437-444. Scaglione F, Panzavolta G. Folate, folic acid and 5-methyltetrahydrofolate are not the same thing. Xenobiotica. 2014;44(5):480-488. Paul C, Brady DM. Comparative Bioavailability and Utilization of Particular Forms of B12 Supplements With Potential to Mitigate B12-related Genetic Polymorphisms. Integr Med (Encinitas). 2017;16(1):42-49. Schwalfenberg GK. Vitamins K1 and K2: The Emerging Group of Vitamins Required for Human Health. J Nutr Metab. 2017;2017:6254836. NIH. Dietary Supplement Fact Sheet For Healthcare Professionals - Omega-3 Fatty Acids. Wong CW. Vitamin B12 deficiency in the elderly: is it worth screening?. Hong Kong Med J. 2015;21(2):155-164. doi:10.12809/hkmj144383 Simes DC, Viegas CSB, Araújo N, Marreiros C. Vitamin K as a Powerful Micronutrient in Aging and Age-Related Diseases: Pros and Cons from Clinical Studies. Int J Mol Sci. 2019;20(17):4150. Published 2019 Aug 25. doi:10.3390/ijms20174150 Termini D, Den Hartogh DJ, Jaglanian A, Tsiani E. Curcumin against Prostate Cancer: Current Evidence. Biomolecules. 2020;10(11):1536. Published 2020 Nov 10. Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int. 2015;94(3):286-295. Islam SU, Ahmed MB, Ahsan H, Lee YS. Recent Molecular Mechanisms and Beneficial Effects of Phytochemicals and Plant-Based Whole Foods in Reducing LDL-C and Preventing Cardiovascular Disease. Antioxidants (Basel). 2021;10(5):784. Published 2021 May 15. doi:10.3390/antiox10050784 National Institutes of Health. Iron: fact sheet for health professionals. Mohn ES, Kern HJ, Saltzman E, Mitmesser SH, McKay DL. Evidence of Drug-Nutrient Interactions with Chronic Use of Commonly Prescribed Medications: An Update. Pharmaceutics. 2018;10(1):36. Published 2018 Mar 20. Moughan PJ. Holistic properties of foods: a changing paradigm in human nutrition. J Sci Food Agric. 2020;100(14):5056-5063. Marra MV, Bailey RL. Position of the Academy of Nutrition and Dietetics: Micronutrient Supplementation [published correction appears in J Acad Nutr Diet. 2019 Feb;119(2):344]. J Acad Nutr Diet. 2018;118(11):2162-2173. NIH Office of Dietary Supplements. Vitamin E. Pendick D. A healthy diet is the key to getting the iron you need. Harvard Health. Paul C, Brady DM. Comparative Bioavailability and Utilization of Particular Forms of B12 Supplements With Potential to Mitigate B12-related Genetic Polymorphisms. Integr Med (Encinitas). 2017;16(1):42-49. Hurrell R, Egli I. Iron bioavailability and dietary reference values. Am J Clin Nutr. 2010;91(5):1461S-1467S. U.S. Department of Health & Human Services and U.S. Department of Agriculture. 2015-2020 Dietary Guidelines for Americans. 2020-2025 Dietary Guidelines for Americans, USDA & Department of Health & Human Services, Health.gov. National Institutes of Health Office of Dietary Supplements. Multivitamin/mineral supplements: Fact sheet for health professionals. Price CT, Langford JR, Liporace FA. Essential Nutrients for Bone Health and a Review of their Availability in the Average North American Diet. Open Orthop J. 2012;6:143-149. doi:10.2174/1874325001206010143 Beeram I, Mortensen SJ, Yeritsyan D, Momenzadeh K, von Keudell A, Nazarian A. Multivitamins and risk of fragility hip fracture: a systematic review and meta-analysis. Arch Osteoporos. 2021;16(1):29. Published 2021 Feb 11. National Center for Complementary and Integrative Health. Saw Palmetto. See Our Editorial Process Meet Our Review Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? 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