The Benefits of B Complex Vitamins

A B complex vitamin usually delivers eight of the B vitamins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folic acid), and B12 (cobalamin). Found naturally in meat, leafy greens, dairy, beans, peas, and whole or fortified grains, B complex vitamins help your body make energy from the food you eat and form red blood cells.

The Benefits of B Complex Vitamins

Each B vitamin is essential to certain bodily functions:

B1 (Thiamine)

• Helps the body use carbohydrates from food to produce energy
• Needed for the health of the brain, muscles, and nervous system
• Critical for the growth, development, and function of cells in the body

B2 (Riboflavin)

• Works with other B vitamins (helps convert B6 into a usable form and aids in niacin production)
• Helps convert food into energy
• Needed for red blood cell production and growth
• Keeps the eyes, nervous system, and skin healthy

B3 (Niacin)

• Aids in the conversion of food into energy
• Helps enzymes in the body function properly by helping the body use other B vitamins and make and repair DNA (the genetic material found in all body cells)
• Needed for the production of hormones, such as sex and stress hormones
• Helps with the function of the digestive and nervous systems and skin

B5 (Pantothenic acid)

• Breaks down fats and carbohydrates for energy
• Plays a role in the production of sex and stress hormones in the adrenal glands and neurotransmitters
• Helps the body use other vitamins, such as riboflavin
• Vitamin B5 is needed for the production of red blood cells and cholesterol

B6 (Pyridoxine)

• Needed by the body to use and store protein and carbohydrates from food (in the form of glycogen, a stored energy in the muscles and liver)

• Required for more than 100 enzyme reactions in the body. It aids in the formation of hemoglobin (a substance in red blood cells that carries oxygen through blood) and neurotransmitters and hormones that influence mood and regulate the body's clock
• Involved in immune function and brain development and function

B7 (Biotin)

• Helps the body convert the fats, carbohydrates, and proteins in the food that you eat into energy
• Needed to make fatty acids
• Promotes growth and bone and hair health

B9 (Folic acid)

• Helps your body make red blood cells
• Needed to help cells make and maintain DNA
• Reduces the risk of birth defects in the brain and spine, such as spina bifida

B12 (Cobalamin)

• Helps keep the nervous system and red blood cells healthy
• Required for the formation of red blood cells and DNA
• Important for protein metabolism

Symptoms of Deficiency

• B1 (thiamine): Weight loss, short-term memory loss, weakness, fatigue, cardiovascular symptoms, irritability, and beriberi.
• B2 (riboflavin): Skin disorders, swelling of the mouth and throat, cracks at the corners of the mouth, swollen, cracked lips, hair loss, sore throat, sensitivity to light.
• B3 (niacin): Digestive problems, canker sores, fatigue, inflamed skin, poor circulation, depression, vomiting, pellagra

• B5: Burning feet, depression, fatigue, insomnia, irritability, stomach pains, upper respiratory tract infections, vomiting
• B5 (pantothenic acid): Depression, difficulty concentration, irritability, muscle weakness, nervousness, short-term memory loss.
• B7 (biotin): Hair thinning or loss, skin rashes around the eyes, nose, mouth, or other mucus membranes. dry eyes, brittle nails, and muscle pain.
• B9 (folate): Diarrhea, forgetfulness, gingivitis, loss of appetite, shortness of breath, irritability, tongue inflammation, gingivitis, and poor growth.
• B12 (cobalamin): Fatigue, weakness, constipation, lack of appetite, weight loss, a type of anemia known as megaloblastic anemia, numbness and tingling in the fingers and toes, and nerve damage.

Food Sources of B Complex Vitamins

To boost your intake of B vitamins, look for the following foods:

• B1 (thiamine): Fortified breakfast cereal, enriched and whole grain products (bread, breakfast cereals, rice, noodles, and flour), wheat germ, pork, trout, black beans, mussels, and tuna.
• B2 (riboflavin): Milk and dairy products, fortified breakfast cereals, beef liver, clams, portobello mushrooms, almonds, and chicken.
• B3 (niacin): Eggs, fish, fortified bread and cereal, rice, nuts, milk and dairy, chicken, beef, turkey, lamb, organ meats, peanuts.
• B5 (pantothenic acid): Meat, avocado, broccoli, kale, eggs, milk, mushrooms, fortified cereals, organ meats, poultry, potatoes, legumes.
• B6 (pyridoxine): Chickpeas, beef liver, tuna, salmon, chicken breast, fortified breakfast cereal, potatoes, turkey, fruits (except citrus), and beef.
• B7 (biotin): Beef liver, egg yolk, wheat germ, pork, beef, sunflower seeds, sweet potato, almonds, whole grain foods, sardines, spinach, and broccoli.
• B9 (folate): Spinach, beef liver, broccoli, brussels sprouts, beans and legumes, asparagus, orange juice, peanuts, avocado, dark leafy greens, fortified cereals, and salmon.
• B12 (cobalamin): Found primarily in animal foods, such as beef liver (and other organ meats), clams and other shellfish, beef, chicken, fish, eggs, milk and other dairy products, and some fortified cereals.

Uses for B Complex Vitamins

With a key role in converting food into fuel, proponents claim that B complex vitamins can help with a variety of conditions, including anxiety, depression, heart disease, and premenstrual syndrome (PMS).

In addition, some people take a vitamin B complex to increase energy, enhance mood, improve memory, boost skin and hair health, and stimulate the immune system.

While most people who eat a varied diet get enough B vitamins from food, some people are at an increased risk of deficiency, particularly those who are over the age of 50, take antacid medication, or have celiac disease, Crohn's disease, gastritis, or other digestive disorders.

If you have had stomach or weight loss surgery, drink alcohol regularly, or follow a vegetarian or vegan diet, you may be more prone to a deficiency.

Pregnant and breastfeeding women may need more vitamins B6, B12, and folic acid.

Possible Side Effects

Although B complex supplements are water-soluble and do not stay in the body for long, large doses of the vitamins in supplement form can cause certain side effects:

B3 (niacin): Skin flushing or pain, elevated blood sugar levels, and liver toxicity.

B6 (pyridoxine): Nerve damage, skin lesions, worsening of kidney function, and increased risk of heart attack, stroke and death in people with diabetes and advanced kidney disease. Recent studies have found that high doses of vitamin B6 were associated with a slightly increased risk of hip fracture and increased risk of lung cancer (when taken with vitamin B12).

B9 (folic acid): Kidney damage, increased insulin resistance in offspring, lower natural killer cell activity in older women, and may be associated with increased risk of some cancers. Can mask the diagnosis of a vitamin B12 deficiency.

B12 (cobalamin): Acne and rosacea in some people. Vitamin B12 has been found to speed the decline in kidney function and increase the risk of cardiovascular events in people with impaired kidney function. High doses of vitamin B12 taken with folic acid have been associated with a greater risk of cancer and mortality.

There is a daily tolerable intake level (UL) for each B vitamin, which is above what most people need. Getting more than the UL increases your chances of side effects.

A Word From Verywell

To stay healthy, most people can get what they need by eating a varied, balanced diet filled with delicious foods naturally rich in B vitamins, such as leafy greens, nuts, beans and legumes, whole grains, lean protein, mushrooms, and eggs. There isn't solid evidence to support taking excessive amounts of B vitamins if you're not deficient in them.

If you're not getting enough of a B vitamin from your diet, taking a vitamin B supplement may be beneficial for some people. Deficiency in B vitamins can cause a number of symptoms, including tiredness, anemia, loss of appetite, depression, abdominal pain, muscle cramps, hair loss, and eczema.

Just be sure to consult your health care provider to find out whether a B complex supplement is right for you (and if so, the appropriate amount considering the total daily amount you are getting from food and supplements). 

_Sources:

Afriyie-Gyawu E, Ifebi E, Ampofo-Yeboah A, Kyte B, Shrestha S, Zhang J. Serum folate levels and fatality among diabetic adults: A 15-y follow-up study of a national cohort. Nutrition. 2016 Apr;32(4):468-73. 

Kim SJ, Zuchniak A, Sohn KJ, et al. Plasma folate, vitamin B-6, and vitamin B-12 and breast cancer risk in BRCA1- and BRCA2-mutation carriers: a prospective study. Am J Clin Nutr. 2016 Sep;104(3):671-7. 

Tio M, Andrici J, Cox MR, Eslick GD. Folate intake and the risk of prostate cancer: a systematic review and meta-analysis. Prostate Cancer Prostatic Dis. 2014 Sep;17(3):213-9. 

Wang R, Zheng Y, Huang JY, Zhang AQ, Zhou YH, Wang JN. Folate intake, serum folate levels, and prostate cancer risk: a meta-analysis of prospective studies. BMC Public Health. 2014 Dec 29;14:1326.

Disclaimer: The information contained on this site is intended for educational purposes only and is not a substitute for advice, diagnosis or treatment by a licensed physician. It is not meant to cover all possible precautions, drug interactions, circumstances or adverse effects. You should seek prompt medical care for any health issues and consult your doctor before using alternative medicine or making a change to your regimen.